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Trimetazidine is an angina medication sold underneath the well-known label esteem Vastarel MR. In annexe, Vastarel MR has sundry other uses proven close to clinical trials.

1. What are the effects of Vastarel MR?

Anti-angina (anti-myocardial ischemia). Vastarel MR (Trimetazidine) improves myocardial glucose utilization as a consequence inhibition of long-chain 3-ketoacyl CoA thiolase liveliness, resulting in decreased fatty acid oxidation and stimulation of glucose oxidation. The inspiration of glucose oxidation wishes improve optimize cellular animation processes, thus maintaining proper verve metabolism during myocardial ischemia. Increases coronary blood flow, reduces the frequency of angina attacks, reduces blood strength fluctuations, does not ground arrhythmias, so it is employed to enjoin angina attacks.

Vastarel is not the first-line treatment on angina, first of all unreliable angina, after an critical myocardial infarction. It is resultant to shoot up together with nitrate drugs (Nitroglycerin, isosorbide dinitrate ...), can up the dispense of these drugs, thereby reducing the side effects of nitrate drugs Immunomodulatory and anticancer: In cells In cancer cells, inhibition of fatty acid oxidation (FAO) alters metabolic processes quintessential after tumor cubicle function and proliferation, thereby inducing apoptosis of these cells. tumor cells. In appendix, vastarel has the skill to stifle the proliferation of fatal cells. In combining, the downer is also reach-me-down to support the treatment of insight disorders, dizziness, tinnitus linked to blood vessel problems, treatment of blood boat deface in the retina.

2. Indications and contraindications of Vastarel

Indications of Vastarel:
Prophylaxis, sympathetic treatment in patients with angina pectoris, old after deep-rooted penetrating myocardial infarction Dizziness deserved to vasomotor causes of view disadvantage Ophthalmology: Harm to blood vessels in the retina Contraindications to Vastarel:
Hypersensitivity to Trimetazidine is a contraindication. Parkinson's patients Stormy renal omission (Clcr < 30ml/min). Significant women , breastfeeding Children

3. Undesirable effects of Vasstarel

In each discrete to anyhow, using Vastarel has caused unwanted effects including:
Dizziness Scanty blood compel when changing bent Allergic incrustation reactions, nodule of lips and eyes, veneer redness, hasty Disorders Rest Digestive disorders : Diarrhea, abdominal ache, dyspepsia, constipation, nausea, vomiting Hepatitis Headache

4. Vasarel (trimetazidine) dosage

For angina In search 20mg tablets: Acknowledge 1 tablet/time, 3 times a daylight with meals. MR 35mg delayed-release tablets: Take 2 tablets/day in the morning and evening 12 hours apart. The following can be reduced to: 2 times a age, 20mg each time. Throughout fondness and discrimination bank on: 2-3 tablets (20mg) or 40-60 drops 2-3 times a day with meals.
With a view anti-cancer effects that are being tested in clinical trials, prescribed through oncologists

5. Notes when using drugs

Enlighten your doctor around any medications you are attractive, medications with a narrative of allergies, pre-existing medical conditions and flow fettle conditions (eg pregnancy, upcoming surgery, ...). Discontinue medication as directed past physician if no answer to treatment after 3 months of service perquisites assessment Be watchful in patients with non-reactionary kidney problems and those during the course of 75 years of majority Do not high-pressure or capitalize on machines Encumbered by one way When overdosing or experiencing offensive effects of the narcotic should notify the doctor or directly go to the nearest medical expertise recompense assign diagnosis and treatment plan.

Customers can promptly operate to Vinmec Health system nationwide to upon or with the hotline here in requital for support.

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